Introduction
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a synthetic compound that activates AMP-activated protein kinase (AMPK), a critical regulator of cellular energy homeostasis. It has been studied for its potential to enhance metabolic processes, improve cardiovascular health, and boost physical performance.
Benefits of AICAR 50mg
AICAR’s activation of AMPK offers several potential research benefits:
Metabolic Regulation: Enhances glucose uptake and insulin sensitivity, potentially aiding research into type 2 diabetes and obesity (Diabetes Journals).
Cardiovascular Health: May reduce blood pressure and improve lipid profiles, supporting studies on cardiovascular disease prevention.
Physical Performance: Increases mitochondrial biogenesis, potentially enhancing endurance, as noted in sports-related research (USADA).
Neuroprotection: Preliminary studies suggest potential benefits for neurodegenerative conditions like Alzheimer’s or Parkinson’s (PMC).
Anti-Inflammatory Effects: Inhibits pro-inflammatory cytokines, useful for research into inflammatory disorders (APExBIO).
Benefit | Description | Research Context |
|---|---|---|
Metabolic Regulation | Enhances glucose uptake and insulin sensitivity | Type 2 diabetes, obesity studies |
Cardiovascular Health | Reduces blood pressure, improves lipid profiles | Cardiovascular disease prevention |
Physical Performance | Increases mitochondrial biogenesis, endurance | Exercise physiology, sports science |
Neuroprotection | Potential benefits for neurodegenerative diseases | Alzheimer’s, Parkinson’s research |
Anti-Inflammatory | Inhibits cytokine production | Inflammatory disorder studies |
Certificate of Analysis
Property | Description |
|---|---|
Chemical Name | 5-Aminoimidazole-4-carboxamide ribonucleotide |
CAS Number | 2627-69-2 |
Molecular Formula | C9H14N4O6P |
Molecular Weight | 338.2 g/mol |
Appearance | White to off-white lyophilized powder |
Purity | ≥98% (HPLC) |
Solubility | Soluble in water |
Storage | Store at -20°C in a dry place, protected from light |
Learn More About AICAR
AICAR: A Review of Its Potential Therapeutic Applications – Overview of AICAR’s mechanisms and potential in metabolic and cardiovascular research (Diabetes Journals).
The Role of AICAR in Exercise Performance and Recovery – Explores AICAR’s effects on endurance and mitochondrial function (USADA).
AMPK Activation by AICAR: Implications for Cancer Therapy – Discusses broader applications, including potential in cancer research (PMC).
