Introduction to Kisspeptin (10 mg)
Kisspeptin, a neuropeptide encoded by the KISS1 gene, plays a central role in regulating the hypothalamic-pituitary-gonadal (HPG) axis and is a key signaling molecule in reproductive endocrine research. The 10 mg formulation is a synthetic decapeptide analog (Kisspeptin-10), supplied as a lyophilized powder intended for reconstitution under controlled laboratory conditions.
Kisspeptin is commonly studied in in vitro and preclinical models focusing on hormonal signaling, endocrine axis stimulation, and neuroendocrine communication pathways.
Key Research Areas
In non-clinical laboratory studies, Kisspeptin has been investigated for its role in:
Activation of gonadotropin-releasing hormone (GnRH) neurons via the GPR54 (KISS1R) receptor
Regulation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release in endocrine feedback models
Onset of puberty, reproductive axis timing, and hypothalamic-pituitary feedback loops
Experimental studies of metabolic signaling, appetite, and neuroendocrine cross-talk
This compound is not intended for therapeutic, diagnostic, or medical use in humans or animals. All research must be conducted in accordance with local and federal regulations.
Certificate of Analysis
| Property | Description |
|---|---|
| Chemical Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| CAS | 374675-21-5 |
| Molecular Formula | C63H83N17O14 |
| Molecular Weight | 1302.44 g/mol |
| CID | 25240297 |
| Appearance | White Lyophilized Powder (reconstituted for injection or oral tablet in research) |
| Purity | ≥98% (verified by HPLC, per USP <621>) |
| Storage | Store at -20°C (lyophilized) or 2–8°C (reconstituted); stable for 24 months |
| Testing Standards | Complies with GMP (21 CFR Part 211), ISO/IEC 17025-accredited lab analysis |
Learn More About Kisspeptin
- “Kisspeptin-10 stimulates gonadotropin release in healthy men” (Dhillo et al., J Clin Endocrinol Metab, 2005).
- “Kisspeptin restores ovulation in women with hypothalamic amenorrhea” (Jayasena et al., J Clin Invest, 2014).
- “Kisspeptin: A novel regulator of reproductive function” (Endocrine Reviews, 2009).
- “Therapeutic potential of kisspeptin in infertility and hypogonadism” (Nature Reviews Endocrinology, 2013).
- “Kisspeptin’s role in puberty and metabolism” (Journal of Endocrinology, 2016).
Research Use Only
This material is supplied strictly for laboratory research and in vitro analytical use only. It is not intended for use in humans or animals, nor should it be misbranded or marketed as a drug, therapeutic agent, supplement, or food product. Proper handling, storage, and disposal are the responsibility of the purchaser.
