What is Semaglutide?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the management of type 2 diabetes. This medication functions by stimulating insulin secretion, thereby helping to control blood sugar levels. It is administered via subcutaneous injection and has gained significant attention due to its efficacy in glycemic control and weight management.
Mechanism of Action
Semaglutide mimics the action of the naturally occurring hormone GLP-1. It binds to the GLP-1 receptors, which results in increased insulin secretion from the pancreas when blood glucose levels are high. Additionally, it inhibits glucagon release, delays gastric emptying, and promotes satiety, thereby reducing appetite and helping in weight management.
Clinical Efficacy and Benefits
Clinical trials have demonstrated that semaglutide significantly reduces HbA1c levels and supports weight loss. Patients using semaglutide have experienced a marked improvement in their glycemic control compared to those on placebo or other antidiabetic medications. The dual benefit of blood sugar control and weight reduction makes semaglutide a valuable option for type 2 diabetes and obesity research.
Certificate of Analysis
Property | Description |
Chemical Sequence | H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
CAS | 910463-68-2 |
Molecular Formula | C187H291N45O59 |
Molecular Weight | 4113.641 g/mol |
CID | 56843331 |
Appearance | White Lyophilized Powder |
Learn More About Semaglutide
- “Semaglutide reduces the absolute risk of major cardiovascular events by 1.5%”
- “As Semaglutide’s Popularity Soars, Rare but Serious Adverse Effects Are Emerging”
- “Glycemic Control, Weight Management, Cardiovascular Safety”
- “Semaglutide in Cardiometabolic Diseases”
- “Efficacy and safety of semaglutide on weight loss in obese or overweight patients without diabetes”