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(generic for Retin-A)


  • Reduces fine lines and wrinkles1,2,3
  • Improves collagen production4,5
  • Treats adult acne6
  • Repairs sun damage7

Background & History

Retin-A (tretinoin) was first approved for medical use in 1962 and is on the World Health Organization’s List of Essential Medicines. Tretinoin is a derivative of Vitamin A and has been shown to improve aging skin and collagen depletion since Vitamin A is a key component to having healthy skin. Tretinoin improves crow’s feet, hydrates the skin, reduces deep lines in the skin, and generates rapid skin cell turnover which ultimately boosts collagen levels.

Taking the Medication and Side Effects

Tretinoin (generic for Retin-A) is a topical cream that is applied at the skin at nightly about 3 times per week. Tretinoin may cause some skin tingling, burning, and mild peeling as a result of the skin creating new layers of skin causes brighter and tighter skin. A medication guide and pharmacy consultation will be provided to you upon receiving this medication.

Research Articles

(1) Do retinoids really reduce wrinkles? – Harvard Health. https://www.health.harvard.edu/staying-healthy/do-retinoids-really-reduce-wrinkles.

(2) Tretinoin Cream: Skin Benefits, How to Use, Side Effects – Healthline. https://www.healthline.com/health/skin/tretinoin.

(3) Effect of Tretinoin on Collagen Formation in Photodamaged Skin. https://www.nejm.org/doi/full/10.1056/NEJM199312303292715.

(4) 9 ways to stimulate collagen production in skin – Medical News Today. https://www.medicalnewstoday.com/articles/317151.

(5) Restoration of collagen formation in photodamaged human skin by …. https://pubmed.ncbi.nlm.nih.gov/8336752/.

(6) Tretinoin for Acne: Usage, Benefits, Efficacy, and Side Effects. https://www.healthline.com/health/tretinoin-for-acne.

(7) How to Repair Sun Damaged Skin: Treatments to Reverse Sun Damage. https://www.vitalskinderm.com/blog/repair-sun-damaged-skin/.

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