USP Compliants

Key Research Areas

Selank is a synthetic heptapeptide derived from the naturally occurring tetrapeptide tuftsin. It is primarily utilized in non-clinical and preclinical research settings to explore its potential neuromodulatory and immunomodulatory properties. Experimental findings from animal models and in vitro studies have suggested the following areas of interest:

• Anxiolytic-Like Activity: Selank has demonstrated potential to modulate stress and anxiety-like behaviors in rodent models without sedative effects, offering a point of comparison to standard reference compounds in anxiolytic assays.

• Cognitive Performance Metrics: Research models have shown improved performance in tasks involving memory retention, attention span, and learning, particularly under stress-induced or fatigue conditions.

• Monoaminergic Modulation: Studies suggest Selank may influence the regulation of neurotransmitters such as serotonin and dopamine in animal subjects, indicating potential relevance in mood stability research.

• Neuroprotection: In oxidative and inflammatory injury models, Selank has exhibited protective effects on neuronal viability and synaptic integrity, offering value for investigations into neurodegenerative disease mechanisms.

• Immunomodulatory Properties: Preclinical research indicates a role in modulating cytokine profiles and enhancing phagocytic responses, with applications in immune system regulation under stressor conditions.

• Stress Adaptation: Selank has been studied for its interaction with the hypothalamic-pituitary-adrenal (HPA) axis and endogenous opioid pathways in animal models, indicating potential utility in understanding physiological stress responses.

Disclaimer: Selank is a research peptide not approved for human or veterinary use. All observed effects are derived from in vitro assays and animal models. These findings do not imply safety, efficacy, or suitability for clinical application. This compound is intended for laboratory research purposes only.