Introduction to Vasoactive Intestinal Peptide (VIP) – 28 Amino Acids
Vasoactive Intestinal Peptide (VIP) is a 28-amino-acid synthetic peptide commonly studied in preclinical and laboratory research. It is being investigated for its roles in various biological systems, including gastrointestinal physiology, neuroimmune signaling, and vascular function. VIP is not approved for human or veterinary use and is intended solely for scientific investigation.
Key Research Areas
Based on in vitro and animal model studies, VIP has been examined in the following areas of research:
Gastrointestinal Barrier Function: Studied for its potential to support epithelial cell proliferation, adhesion, and repair in intestinal tissue.
Microbiome Support: Investigated for selective antimicrobial activity and its influence on the growth of commensal gut bacteria.
Gastric Secretion Modulation: Explored for its regulatory role in gastric acid production and electrolyte absorption in intestinal research models.
Smooth Muscle Relaxation: Studied for its effect on intestinal and bronchial muscle tone in organ-specific models.
Vasodilation: Evaluated for its capacity to relax vascular smooth muscle and modulate regional blood flow.
Circadian Rhythm Regulation: Researched for its influence on sleep-wake signaling in studies involving the suprachiasmatic nucleus.
Immune Response Modulation: Studied for its effects on cytokine regulation, including the suppression of pro-inflammatory markers.
Neuroendocrine-Immune Interaction: Investigated in the context of cross-communication between the nervous, immune, and endocrine systems.
Embryonic Development: Explored for its regulatory effects during neural tube development in developmental biology models.
Research Use Disclaimer:
This material is supplied for laboratory and research use only. It is not for human or veterinary use, not for diagnostic or therapeutic purposes, and is not approved by the FDA or any other regulatory agency. Use only in accordance with applicable local, state, and federal laws.
Certificate of Analysis
| Property | Description |
|---|---|
| Chemical Sequence | H-Asn-His-Asp-Gln-Asp-Val-Val-His-Leu-Ser-Arg-Arg-Asn-Leu-Gly-Leu-Arg-Gln-Gln-Gln-Arg-Lys-Leu-Gln-Asp-Asn-Pro-Arg-Arg-Gln-NH2 |
| CAS | 106479-53-8 |
| Molecular Formula | C129H210N40O36 |
| Molecular Weight | Approximately 2670.5 g/mol |
| Appearance | White Lyophilized Powder |
Research Use Only:
VIP is intended strictly for in vitro testing and laboratory experimentation. It is not intended for human or animal medical use. It is not a drug, food, or cosmetic and should not be misbranded, misused, or mislabeled as such
