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P-21 5mg
Original price was: $39.99.$29.99Current price is: $29.99.Product Purpose:
Enhanced Neurogenesis: Promotes proliferation and differentiation of neural progenitor cells in the hippocampal dentate gyrus, increasing new neuron formation and integration into neural networks, as shown in 3xTg-AD mice.
Improved Cognitive Function: Enhances learning, short-term memory, and spatial reference memory in normal and AD-model mice, potentially through increased BDNF and CREB activity.
Neuroprotection: Reduces tau hyperphosphorylation and Aβ plaque accumulation, slowing AD progression in transgenic models, and protects neurons from inflammatory damage.
Synaptic Plasticity: Increases expression of synaptic markers (synapsin, PSD-95, MAP2), supporting neurotransmitter release, synaptic organization, and dendritic stability, critical for memory and learning.
Reduced Neuroinflammation: Decreases glial fibrillary acidic protein (GFAP) levels, indicating reduced neuroinflammation in AD models, potentially mitigating neuronal damage.
Potential Appetite Regulation: May reduce food intake via α-MSH stimulation, though evidence is preliminary and requires further investigation.
Research Use Only:
P21 is intended strictly for in vitro testing and laboratory experimentation. It’s not intended for human or animal medical use. It’s not a drug, food, or cosmetic and should not be misbranded, misused, or mislabeled as such.
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Pinealon 10mg
Original price was: $34.99.$14.99Current price is: $14.99.Product Purpose:
Pinealon is a synthetic tripeptide composed of Glu-Asp-Arg. It is designed to explore its potential benefits in modulating gene expression and protecting neurons. Research indicates that it may improve cognitive functions and protect against hypoxia.
Research Use Only:
Pinealon is intended strictly for in vitro testing and laboratory experimentation. It’s not intended for human or animal medical use. It’s not a drug, food, or cosmetic and should not be misbranded, misused, or mislabeled as such.
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Pinealon 20mg
Original price was: $34.99.$29.99Current price is: $29.99.Product Purpose:
Pinealon is a synthetic tripeptide composed of Glu-Asp-Arg. It is designed to explore its potential benefits in modulating gene expression and protecting neurons. Research indicates that it may improve cognitive functions and protect against hypoxia.
Research Use Only:
Pinealon 20mg is intended strictly for in vitro testing and laboratory experimentation. It’s not intended for human or animal medical use. It’s not a drug, food, or cosmetic and should not be misbranded, misused, or mislabeled as such.
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PNC-27 5mg
Original price was: $129.99.$89.99Current price is: $89.99.Product Purpose:
Selective Anticancer Activity: Induces necrosis in a variety of cancer cell lines, including pancreatic, breast, ovarian, cervical, and leukemia cells, while sparing normal cells like fibroblasts and lymphocytes, due to its specific binding to HDM-2 on cancer cell membranes.
Broad-Spectrum Efficacy: Effective against both solid tumors (e.g., pancreatic, colon, lung) and non-solid tumors (e.g., acute myeloid leukemia), including p53-null cells, broadening its potential therapeutic scope.
Rapid Action: Causes cancer cell lysis within minutes to hours by forming transmembrane pores, offering a faster mechanism of action compared to apoptosis-based therapies.
Synergistic Potential: Enhances the efficacy of other anticancer agents, such as paclitaxel and methotrexate, by reducing their IC50 values, potentially improving outcomes in combination therapies.
Tumor Suppression in Vivo: Demonstrates tumor eradication in animal models, such as nude mice with pancreatic cancer xenografts, without significant toxicity to healthy tissues.
Potential for Targeted Delivery: When conjugated to nanoparticles (e.g., single-walled carbon nanotubes), PNC-27 enhances focal accumulation in cancer tissue, improving therapeutic outcomes in models like colon adenocarcinoma.
Research Use Only:
PNC-27 is intended strictly for in vitro testing and laboratory experimentation. It’s not intended for human or animal medical use. It’s not a drug, food, or cosmetic and should not be misbranded, misused, or mislabeled as such.